A Randomized Trial of Nortriptyline for Smoking Cessation
نویسندگان
چکیده
منابع مشابه
Bupropion for smoking cessation: a randomized trial.
BACKGROUND Bupropion hydrochloride is recommended for smoking cessation; however, there have been relatively few clinical trials examining its efficacy. METHODS A total of 244 current smokers were enrolled in an outpatient randomized blinded smoking cessation trial conducted at the San Francisco Veterans Affairs Medical Center, San Francisco, Calif. Of the 244 participants, 121 received a 7-w...
متن کاملA controlled trial of nortriptyline, sustained-release bupropion and placebo for smoking cessation: preliminary results.
PURPOSE AND METHODS Cognitive behavior therapy (CBT) constitutes the basis of smoking cessation programs. Quitting rates are usually increased by the concomitant use of CBT and pharmacotherapy. There are studies showing the efficacy of bupropion and nortriptyline compared to placebo, but there is just one published comparison between these drugs, unfortunately with low power to detect significa...
متن کاملA randomized controlled trial of financial incentives for smoking cessation.
BACKGROUND Although 435,000 Americans die each year of tobacco-related illness, only approximately 3% of smokers quit each year. Financial incentives have been shown to be effective in modifying behavior within highly structured settings, such as drug treatment programs, but this has not been shown in treating chronic disease in less structured settings. The objective of this study was to deter...
متن کاملExenatide Once Weekly for Smoking Cessation: A Randomized Clinical Trial
Background: Cigarette smoking is the greatest preventable cause of morbidity and premature mortality in the US. Approved pharmacological treatments for smoking cessation are only marginally effective, underscoring the need for improved pharmacotherapies. Glucagon-like peptide-1 (GLP-1) is produced in the intestinal L-cells and in the hindbrain nucleus solitarius. GLP-1 functions to maintain glu...
متن کاملNortriptyline plus nicotine replacement versus placebo plus nicotine replacement for smoking cessation: pragmatic randomised controlled trial.
OBJECTIVE To test the efficacy of nortriptyline plus nicotine replacement therapy compared with placebo plus nicotine replacement therapy for smoking cessation. DESIGN Pragmatic randomised controlled trial. SETTING National Health Service stop smoking service clinics. PARTICIPANTS 901 people trying to stop smoking. INTERVENTIONS Participants chose their nicotine replacement product, inc...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 1998
ISSN: 0003-9926
DOI: 10.1001/archinte.158.18.2035